Tocris mg132
Webb7 sep. 2024 · HIF-1α clone H1α67, HIF-1α clone EP1215Y, anti-mouse and -rabbit horseradish peroxidase-conjugated secondary antibodies were from Merck Millipore, Darmstadt, Germany. Src-Inhibitor PP2 was purchased from Sigma-Aldrich (#P0042), Darmstadt, Germany. p38 MAPK inhibitor (SB203580), MG132 and MG101 were from … Webb产品描述 . MG132 (MG-132, Z-Leu-Leu-Leu-al, Z-Leu-Leu-Leu-CHO)是强效的 、 可逆的 、 细胞通透性proteasome抑制剂(IC 50 = 100 nM),抑制20S蛋白酶体的ZLLL-MCA降解活性时,比ZLLal有效1000多倍。 MG132也可以抑制细胞周期和细胞周期蛋白降解所需要的calpain (IC 50 = 1.2 μM),并诱导PC12细胞中神经突增生。
Tocris mg132
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WebbProduct Information Product Usage Information Bortezomib is supplied as a lyophilized powder. For a 1 mM stock, reconstitute the 2.5 mg in 6.51 ml DMSO. Working concentrations and length of treatment can vary depending on the desired effect, but it is typically used at 1-1000 nM for 2-48 hours. WebbCompany Tocris Bioscience; Price Pricing Info Supplier Page View Company Product Page; Catalog Number 6033/10; Quantity 10 mg; Purity 0.98; Molecular Weight 475.63; …
WebbI am planning to treat my cells (transiently transfected and I generally process transfected cells after 48 hours of transfection) with MG132 for preventing degradation. From literature, 10 um ... Webb「MG132」。富士フイルム和光純薬株式会社は、試験研究用試薬・抗体の製造販売および各種受託サービスを行っています。先端技術の研究から、ライフサイエンス関連、有 …
WebbNational Center for Biotechnology Information WebbMG132 acts as a powerful apoptotic agent in several tumor cell lines, and much of the MG132 activity has been attributed to NF-κB inhibition through the inhibition of IκB degradation. 24 Since the degradation of inhibitors of κB proteins (IκBα and IκBβ) is essential for the canonical pathway of NF-κB activation and the aberrant expression of …
Webb1 jan. 2024 · To further determine whether the ISR inhibits necroptosis, we pre-stressed BMDMs with additional SG inducers including brefeldin A, tunicamycin, MG132, arsenite, …
WebbMG 132, Tocris Bioscience™. Proteasome and calpain inhibitor. Inhibits NF-κB activation. Manufacturer: Tocris Bioscience 1748/5. Catalog No. 17-485. $147.00 / Each. Qty. Add … laboratorio pathology macaeWebb6 jan. 2024 · To test whether PRKD3 stabilizes CLU protein through either UPS or ALP or both, proteasomal inhibitor‐MG132 and lysosomal inhibitor‐chloroquine (CQ) were used. The results show that CQ but not MG132 treatment can alleviate the degradation of CLU upon depletion of PRKD3, suggesting that PRKD3 stabilizes CLU via protecting CLU from … promo code for first leafWebbPurity: ≥98%. Storage: Store at -20°C. CAS No: 1211877-36-9. The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. Tocris products are intended for laboratory research use only, unless stated otherwise. laboratorio plp groupWebb28 nov. 2024 · MG132 is a well-characterized proteasome inhibitor that induces caspase-8-dependent osteosarcoma-cell apoptosis ( 14 ). Moreover, MG132 was reported to inhibit the transcriptional activity and expression of the oncogenic transcription factor forkhead box M1, promoting apoptosis in several human cancer types ( 15 ). promo code for first american home warrantyWebb( R )-MG 132 is a potent 20S proteasome inhibitor (IC 50 = 0.22 nM). Exhibits cytostatic and cytotoxic effects in tumor cells in vitro. Technical Data for ( R )-MG 132 The technical … promo code for find parkingWebbMG132 is a potent, reversible, and cell-permeable proteasome inhibitor (K i = 4 nM). It belongs to the class of synthetic peptide aldehydes. It reduces the degradation of … promo code for flashfoodWebb11 jan. 2024 · Select the department you want to search in ... promo code for first lite