site stats

Olfm4 and cancer

Web02. maj 2024. · Conclusion: OLFM4 is induced by the LGR5-Wnt signaling pathway and is strongly associated with aggressive tumor progression and poor prognosis in HCC by regulating STAT3-induced tumor cell proliferation and cancer stem cell–like property. Therefore, OLFM4 is a novel prognostic predictor and a potential therapeutic target for … WebChronic inflammatory bowel disease (IBD) is strongly associated with the development of colitis-associated tumorigenesis (CAT). Despite recent advances in the understanding of …

OLFM4 Is a Robust Marker for Stem Cells in Human

Web28. sep 2010. · The OLFM4 gene was first identified by virtue of its high expression in colon cancer cells through analysis of Cancer Genome Anatomy Project data from the United States National Cancer Institute. The gene was originally cloned from human haematopoietic myeloid cells and mapped to chromosome 13q14.3 [].It consists of five … Web10. jan 2024. · Chemoresistance was observed by in vitro analysis of tumor cell lines with forced expression of OLFM4. In an assessment of tissue specimens from 80 patients … lady gaga parents net worth https://prosper-local.com

Microarrays Free Full-Text Integrating Colon Cancer Microarray …

Web18. jul 2024. · Cancer molecular subtyping (describing cancer subtypes) is important not least because of its potential relevance to choice of treatment [1,2].In the case of Colon Cancer, classifications of colorectal cancers (CRC) can be subdivided into 3–6 subtypes, based on gene expression profiles [1,2,3,4].Alternatively, CRC has been shown to divide … WebOLFM4 expression has been studied in several tumor types including gastric, colorectal, lung, and endometrioid cancers where it has been suggested to be an independent … Web01. mar 2024. · The olfactomedin 4 (OLFM4) gene has been analyzed as a tumor-suppressor gene and a putative biomarker in many cancers. In our study, we analyzed … property for sale in handsworth birmingham

OLFM4-RET fusion is an oncogenic driver in small intestine ...

Category:CD115− monocytic myeloid-derived suppressor cells are …

Tags:Olfm4 and cancer

Olfm4 and cancer

OLFM4 deficiency delays the progression of colitis to colorectal …

Web20. feb 2024. · 并且有文献指出，OLFM4在与富含亮氨酸重复序列G蛋白偶联受体5（leucinerich-repeat-containing G-protein-coupled receptor 5，Lgr5）关联的结肠癌干细胞中有表达[14-15]，而Lgr5与肿瘤的恶性程度直接相关，这也进一步证明了OLFM4与结肠癌肿瘤的分期相关，或许可将OLFM4 作为结肠癌 ... Web21. okt 2024. · OLFM4 expression is frequently lost or reduced in human small intestine adenocarcinoma and is correlated with tumor grade and stage. OLFM4 mRNA is …

Olfm4 and cancer

Did you know?

Web02. maj 2024. · Moreover, the cancer stem cell-like property of OLFM4 mediated by leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5), known as an intestinal stem …

Web29. apr 2024. · These findings suggest that OLFM4 could be a useful marker for cancer precursors or early-stage CRC, and genetic manipulation of OLFM4 expression could be … Web10. jan 2007. · Overexpression of the olfactomedin 4 (OLFM4 GW112,/hGC−1) gene was recently reported to inhibit various apoptotic pathways and promote proliferation of …

Web14. mar 2016. · Previous studies have shown that OLFM4 protein expression has been reduced or lost in a portion of human colon cancers, with loss being more prevalent in … Web19. nov 2015. · Loss of olfactomedin 4 (OLFM4) gene expression is associated with the progression of human prostate cancer, but its role and the molecular mechanisms involved in this process have not been ...

WebCytoreductive surgery and chemotherapy continue to be the mainstay of ovarian cancer treatment. However, as mortality from advanced ovarian cancer remains very high, novel therapies are required to be integrated into existing treatment regimens. Immunotherapy represents an alternative and rational therapeutic approach for ovarian cancer based on …

WebOLFM4 is proved to as a functional target for miR-590. PMID: 28012926; Olfactomedin 4 is a novel tumor marker for triple-negative breast cancer for predicting and prognosis. PMID: 27939521; OLFM4 is downregulated by miR-486-5p, which contributes to … lady gaga perfect illusion acousticWeb15. mar 2024. · Low expression of OLFM4 promoted lymph node and distant metastasis resulting in a poor prognosis of triple-negative breast cancer patients and low expression of OLFM4 in early gastric cancer was ... lady gaga perfect illusion t shirtWebProtein function (UniProt)i. Useful information about the protein provided by UniProt. May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leu kemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 ... lady gaga perfect illusion shortsWebPancreatic ductal adenomcarcinoma (PDAC) is one of the most lethal forms of cancer with a 5-year survival rate of 8%. To determine the composition of different cell types in PDAC, we performed ... lady gaga pays tribute to june brownWeb10. apr 2024. · Gastric cancer is a dominant source of cancer-related death around the globe and a serious threat to human health. However, there are very few practical diagnostic approaches and biomarkers for the treatment of this complex disease. ... SFRP4, CDH17, FAP, CLDN1, and OLFM4 were of the highest LogFC values among the upregulated … property for sale in hanslope rightmoveWeb01. mar 2007. · The results indicate that OLFM4 promotes proliferation of PANC‐1 cells by favoring transition from the S to G2/M phase and inhibition of small interfering RNA did not promote apoptosis. Induction of olfactomedin 4 (OLFM4GW112/hGC‐1) in cancer cells was recently reported to have a novel antiapoptotic action via binding to the potent apoptosis … property for sale in hapton lancashireWebP16、OLFM4在宫颈上皮内瘤变中的表达及其诊断意义.docx,P16、OLFM4在宫颈上皮内瘤变中的表达及其诊断意义 摘 要 背景与目的：宫颈上皮内瘤变是常见妇科疾病，但因其表现多样化、易与非瘤变性病变混淆，因此需要寻找更准确、特异、敏感的标志物来辅助临床诊断。 lady gaga outfits red carpet