TīmeklisFunction. Lysosomal membrane glycoprotein which plays an important role in lysosome biogenesis, autophagy, and cholesterol homeostasis ( By similarity ). Also plays an important role in NK-cells cytotoxicity. Mechanistically, participates in cytotoxic granule movement to the cell surface and perforin trafficking to the lytic granule. Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, … Skatīt vairāk Residing primarily across lysosomal membranes, these glycoproteins consist of a large, highly glycosylated end with N-linked carbon chains on the luminal side of the membrane, and a short C-terminal tail exposed to the Skatīt vairāk LAMP1 and LAMP2 glycoproteins comprise 50% of all lysosomal membrane proteins, and are thought to be responsible in part for maintaining lysosomal integrity, pH and catabolism. … Skatīt vairāk • Cluster of differentiation Skatīt vairāk • LAMP1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • PDBe-KB provides an overview of all the structure information available in the PDB for Human Lysosome-associated membrane glycoprotein 1 Skatīt vairāk LAMP1 expression on the surface of tumor cells has been observed for a number of different cancer types, particularly in highly metastatic cancers such as pancreatic cancer Skatīt vairāk • Chang MH, Karageorgos LE, Meikle PJ (2003). "CD107a (LAMP-1) and CD107b (LAMP-2)". Journal of Biological Regulators and Homeostatic Agents. 16 (2): 147–51. PMID 12144129. • Schleutker J, Haataja L, Renlund M, Puhakka L, Viitala J, Peltonen L, … Skatīt vairāk
LAMP1 (D2D11) XP® Rabbit mAb Cell Signaling Technology
Tīmeklis2024. gada 21. marts · LAMP1 Antibody (H4A3) is recommended for detection of LAMP-1 of mouse, rat and human origin by WB, IP, IF, IHC (P) and FCM; also reactive with additional species, including monkey Anti-LAMP1 Antibody (H4A3) is available conjugated to agarose for IP; HRP for WB, IHC (P) and ELISA; and to either … TīmeklisLAMP1 (CD107a, lysosome-associated membrane protein-1) together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane. LAMP1 is a heavily glycosylated membrane protein which contains a putative signal peptide, 18 sites for N-linked glycosylation, a single membrane … trim on doors ideas
Anti-LAMP1 antibody [1D4B] (ab25245) Abcam
Tīmeklis兔多克隆抗体to LAMP1 - Lysosome Marker 宿主 Rabbit 经测试应用 适用于: IHC-P, WB more details 种属反应性 与反应: Human 预测可用于: Mouse, Rat, Chicken, Hamster, Cow, Cat, Dog, Xenopus laevis, … TīmeklisLAMP1+TRAIL+ astrocytes limit inflammation in the CNS by inducing T cell apoptosis through TRAIL–DR5 signalling. In homeostatic conditions, the expression of TRAIL in astrocytes is driven by ... Tīmeklis2024. gada 21. marts · LAMP1 (Lysosomal Associated Membrane Protein 1) is a Protein Coding gene. Diseases associated with LAMP1 include Mumps and Chediak-Higashi Syndrome.Among its related pathways are Innate Immune System and Cytoskeletal Signaling.Gene Ontology (GO) annotations related to this gene include enzyme … trim on imovie keyboard shortcut