WebFeb 19, 2024 · Guanylate-binding proteins (GBP1 and GBP5) are known to be important for host resistance against porcine reproductive and respiratory syndrome virus (PRRSV) infection. In this study, the effects of polymorphisms in GBP1 (GBP1E2 and WUR) and GBP5 on host immune responses against PRRSV were investigated to elucidate the … WebFeb 2, 2024 · Background: Recently, we have shown that seven genes, namely GBP5, IRS2, KRT4, LINCOO707, MRPL55, RRS1 and SLC4A11, have prognostic power for the overall survival in ovarian cancer (OC). Methods: We present an analysis on the association of these genes with any phenotypes and mutations indicative of involvement in female …
GBP5 protein may play a key role in suppressing …
WebGuanylate-binding protein (GBP) 5 is an interferon (IFN)-inducible cellular factor reducing HIV-1 infec- ... Finally, we have recently shown that GBP5 reduces HIV-1 infectivity by interfering with maturation and virion 2092 Cell Reports 27, 2092–2104, May 14, 2024 ª 2024 The Author(s). WebApr 3, 2024 · The GBP5 protein levels of aTB patients were significantly higher than those of non-tuberculosis patients (p < 0.001), and the area under the ROC curve of the GBP5 assay for aTB diagnosis was 0.76. nature\u0027s way zinc lozenges echinacea
Whole blood GBP5 protein levels in patients with and …
WebMar 26, 2024 · Predicted to enable GTP binding activity; GTPase activity; and protein homodimerization activity. Involved in positive regulation of cytokine production and positive regulation of innate immune response. Acts upstream of or within cellular response to interferon-gamma and response to bacterium. Located in cytoplasmic vesicle. … WebOct 14, 2024 · Guanylate binding protein 5 (GBP5) belongs to the GTPase subfamily, which is mainly induced by interferon gamma (IFN-γ) and is involved in many important cellular … WebApr 13, 2016 · Our finding that GBP5 protein levels in macrophages from different blood donors correlate with infectious HIV-1 production over several orders of magnitude (r 2 = … nature\u0027s way zoominfo